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Figure 3 | Journal of Biomedical Science

Figure 3

From: The ubiquitin–proteasome system and signal transduction pathways regulating Epithelial Mesenchymal transition of cancer

Figure 3

Representation of EMT regulation by β-catenin. β-catenin induces transcription of EMT-promoting proteins. Resulting adherens junctions dissolution makes available further β-catenin molecules for transcriptional activity except if ubiquitination and proteasomal degradation restrains this activity. Fibroblast Growth Factor (FGF) co-operates in β-catenin transcription (shown as a double edge arrow).

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