Figure 3From: Mechanisms of the antinociceptive action of (−) Epicatechin obtained from the hydroalcoholic fraction of Combretum leprosum Mart & Eic in rodentsPossible mechanisms of EPI. The EPI could act through direct action on serotonin receptors, opioids, acetylcholine or noradrenaline. However, this action might be indirect through the inhibition of glutamate release.Back to article page