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Figure 2 | Journal of Biomedical Science

Figure 2

From: The highly conserved 5' untranslated region as an effective target towards the inhibition of Enterovirus 71 replication by unmodified and appropriate 2'-modified siRNAs

Figure 2

Cytotoxicity assay of RD cells transfected with unmodified and 2′-modified siRNAs. RD cells were transfected with 100 nM of various siRNAs. The mock transfection control was carried out without the addition of siRNA. ‘Scr’ represents RD cells transfected with 100 nM of scrambled siRNA using 0.25 μl of LipofectamineTM 2000. Positive control represents RD cells transfected with 2.5 μl of LipofectamineTM 2000. All data are presented as means ± SD from three independent experiments, each performed in triplicate. *P < 0.05, compared with mock transfection control at 24, 48, and 72 h post-transfection, respectively. The data from the cells transfected with unmodified and 2′-modified siRNAs showed no significant difference compared to the mock transfection control (P > 0.05).

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