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Figure 4 | Journal of Biomedical Science

Figure 4

From: Characterization of Mg2+-regulated TRPM7-like current in human atrial myocytes

Figure 4

TRPM7-like current down-regulation by intracellular Mg2+. Mean data (± S.E.M., n-cells/patients) of up-regulated and additionally unmasked TRPM7-like outward (+80 mV) and inward (-120 mV) current amplitude, respectively, in the presence (A and B) or absence (C and D) of extracellular divalent cations, when different Mgi2+ in each dialysis solution was used, as indicated (in mM). Dot line indicates endogenous current density at rupture, which varied between 1.51 and 1.63 pA/pF at +80 mV, and -0.25 and -0.32 pA/pF at -120 mV. *P<0.001 vs. current value in Mgi2+-chelated myocytes when ANOVA was used.

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