Rapid compensatory changes in the expression of EAAT-3 and GAT-1 transporters during seizures in cells of the CA1 and dentate gyrus

Table 1 Seizure behavior of the three groups of rats following intra-rEC administration of 4-AP (10 nmol, n = 5 per group)

The values represent seizure behavior according to the modified Racine Scale [23]: 0, behavioral arrest (motionless), piloerection, excitement and rapid breathing; 1, movement of the mouth, lips tongue and vibrissae, salivation; 2, head clonus and eye clonus; 3, forelimb clonus, “wet dog shakes”; 4, clonic rearing; 5, clonic rearing with loss of postural control and uncontrolled jumping.
The rats were sacrificed 30 (A), 60 (B) or 180 (C) min after 4-AP injection.

ISSN: 1423-0127