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Table 1 Seizure behavior of the three groups of rats following intra-rEC administration of 4-AP (10 nmol, n = 5 per group)

From: Rapid compensatory changes in the expression of EAAT-3 and GAT-1 transporters during seizures in cells of the CA1 and dentate gyrus

Behavior after 4 AP Injection
RAT Minutes
15 30 45 60 120 180
15 (A) 0/1/2/3 0/1/2/3     
610 (B) 0/1/2 0/1/2/3/4 0/1/2/3/4 0/1/2/3   
1115 (C) 0/1/2/3 1/2/3/4 0/1/2/3/4 0/1/2/3/4 0/1/2/3 0/1/2/3
  1. The values represent seizure behavior according to the modified Racine Scale [23]: 0, behavioral arrest (motionless), piloerection, excitement and rapid breathing; 1, movement of the mouth, lips tongue and vibrissae, salivation; 2, head clonus and eye clonus; 3, forelimb clonus, “wet dog shakes”; 4, clonic rearing; 5, clonic rearing with loss of postural control and uncontrolled jumping.
  2. The rats were sacrificed 30 (A), 60 (B) or 180 (C) min after 4-AP injection.