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Figure 1 | Journal of Biomedical Science

Figure 1

From: The role of PML ubiquitination in human malignancies

Figure 1

Summary of the PML ubiquitination/degradation pathways. These pathways are activated by extracellular or intracellular stimuli, primed by distinct PML posttranslational modifications, mediated by indicated E3 ligases, and perturbed in different types of human cancers. Unidentified E3 ligases are shown by question marks.

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Journal of Biomedical Science

ISSN: 1423-0127