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Figure 1 | Journal of Biomedical Science

Figure 1

From: Tumour necrosis factor alpha downregulates human hemojuvelin expression via a novel response element within its promoter

Figure 1

Effect of acute inflammation on hepatic gene expression in wild-type and Hfe KO mice. A) IL-6 and TNF-α mRNA expression levels were analysed by real time PCR. B) Hepcidin 1 and Hjv mRNA levels were analysed by RT-PCR. C) BMP-2, BMP-4, BMP-6, and TGF-β mRNA expression were analysed by RT-PCR. Data are mean ± SEM (n = 5).*p <0.05, **p <0.01, ***p <0.001 in LPS-injected mice compared to saline-injected controls.

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