Table 2 Eight single nucleotide polymorphisms in the IL12B gene identified from 471 Graves disease patients with or without Graves ophthalmopathy
SNPs | Position in IL12 B | Chromosome position | Alleles | HWpval | MAF |
|---|---|---|---|---|---|
rs2195940 | Intron 5 | 158744352 | C:T | 0.88 | 0.04 |
rs2853696 | Intron 5 | 158744660 | G:G | 1.00 | 0.00 |
rs2421047 | Intron 4 | 158746307 | A:G | 0.53 | 0.48 |
rs2853694 | Intron 3 | 158749088 | A:C | 0.44 | 0.31 |
rs2569254 | Intron 1 | 158751249 | C:T | 1.00 | 0.16 |
rs1003199 | Intron 1 | 158755566 | C:T | 0.56 | 0.37 |
rs7709212 | Promoter | 158764177 | C:T | 0.22 | 0.49 |
rs6868898 | Promoter | 158764420 | C:T | 0.54 | 0.37 |