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Table 2 Eight single nucleotide polymorphisms in the IL12B gene identified from 471 Graves disease patients with or without Graves ophthalmopathy

From: Association of IL12B polymorphisms with susceptibility to Graves ophthalmopathy in a Taiwan Chinese population

SNPs Position in IL12 B Chromosome position Alleles HWpval MAF
rs2195940 Intron 5 158744352 C:T 0.88 0.04
rs2853696 Intron 5 158744660 G:G 1.00 0.00
rs2421047 Intron 4 158746307 A:G 0.53 0.48
rs2853694 Intron 3 158749088 A:C 0.44 0.31
rs2569254 Intron 1 158751249 C:T 1.00 0.16
rs1003199 Intron 1 158755566 C:T 0.56 0.37
rs7709212 Promoter 158764177 C:T 0.22 0.49
rs6868898 Promoter 158764420 C:T 0.54 0.37
  1. SNP positions in the IL12B gene were numbered upstream (+) or downstream (−) from the IL12B transcription initiation site. Chromosome positions were referred to the sequence of NCBI database (built 37.1). SNP, single nucleotide polymorphism; Hwpval, Hardy-Weinberg equilibrium P value; MAF, minor allele frequency.