Table 5 Summary of multifactor dimensionality reduction (MDR) models for gene-gene interaction in male Graves disease patients with Graves ophthalmopathy
Number of factors | Best candidate model | Balance accuracy | CV consistency | X 2 | P value | Odds ratio (95%CI) |
|---|---|---|---|---|---|---|
1 | rs1003199 | 59.47% | 100/100 | 7.53 | 6.00×10-3 | 2.27 (1.26-4.10) |
2 | rs2195940 rs1003199 | 59.50% | 76/100 | 7.67 | 6.00×10-3 | 2.30 (1.27-4.17) |
3 | rs1003199 rs7709212 rs6868898 | 61.40% | 100/100 | 10.52 | 1.20×10-3 | 2.59 (1.45-4.62) |
4 | rs2853694 rs1003199 rs7709212 rs6868898 | 53.28% | 100/100 | 12.47 | 4.00×10-4 | 2.82 (1.58-5.06) |