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Table 5 Summary of multifactor dimensionality reduction (MDR) models for gene-gene interaction in male Graves disease patients with Graves ophthalmopathy

From: Association of IL12B polymorphisms with susceptibility to Graves ophthalmopathy in a Taiwan Chinese population

Number of factors Best candidate model Balance accuracy CV consistency X 2 P value Odds ratio (95%CI)
1 rs1003199 59.47% 100/100 7.53 6.00×10-3 2.27 (1.26-4.10)
2 rs2195940 rs1003199 59.50% 76/100 7.67 6.00×10-3 2.30 (1.27-4.17)
3 rs1003199 rs7709212 rs6868898 61.40% 100/100 10.52 1.20×10-3 2.59 (1.45-4.62)
4 rs2853694 rs1003199 rs7709212 rs6868898 53.28% 100/100 12.47 4.00×10-4 2.82 (1.58-5.06)