Figure 2

Lung tissue sections of rats. Protective antigen (PA) and lethal toxin (LT) (0.25 mg/kg) were injected into Sprague Dawley rats for four hours to induce pathogenic responses. Lung tissue sections from the PA- (A-1,3, B-1,3) and the LT- (A-2,4, B-2,4) treated rats were stained with hematoxylin and eosin (A) and anti-fibrinogen/fibrin antibodies (B). The asterisks * refer to the brown-colored regions that indicate the localization of the anti-fibrinogen/fibrin antibodies (B-4).