Caspase-3 and caspase-7 activity in transfected cells under hypoxia. Transfected cells were incubated under hypoxia for 8 hours. Cells were harvested and Caspase-3/7 activity were determined using the Caspase-3 and Caspase-7 Assay Kit by flow cytometry. (A) Flow cytometry results for caspase-3/7 activity. (B) Histogram of the percentage of caspase-3/7 activity among different groups. Control indicated miR-negative control. The data were presented as the means ± SD. Columns, mean of three independent experiments; bars, SD.