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Table 2 Identified micro-RNAs mediated modulation of host response during Mycobacterial infection/ stimulation

From: Current understanding on micro RNAs and its regulation in response to Mycobacterial infections

Micro-RNAs

Identified regulation mechanism

Reference

miR-29

Suppress the IFN-γ production by targeting IFN-γ mRNA

Ma et al.[48]

miR-29 and Let-7e

Inhibit the apoptosis by caspases 3 and 7 (major effector caspases)

Sharbati et al.[47]

miR 125b

Block the TNF-α biosynthesis

Rajaram et al.[49]

miR-155

Enhance the TNF-α biosynthesis

Rajaram et al.[49]

miR-155

Repress Bach1 and SHIP1 to support the dormancy and survival of M. tuberculosis in host

Kumar et al.[51]

miR-99b

Negatively regulate the production of proinflammatory cytokine that leads to reduced growth of M. tuberculosis

Singh et al,[50]