Table 7 Prediction performance of in silico tools in the test set
| Â | CoDP | MAPP for MSH6 | SIFT | PolyPhen2 HumVar | PolyPhen2 HumDiv |
|---|---|---|---|---|---|
TP | 5 | 4 | 4 | 5 | 5 |
TN | 4 | 4 | 4 | 2 | 1 |
FP | 0 | 0 | 0 | 2 | 3 |
FN | 0 | 1 | 1 | 0 | 0 |
PPV | 5/5 | 4/4 | 4/4 | 5/7 | 5/8 |
NPV | 4/4 | 4/5 | 4/5 | 2/2 | 1/0 |
Sencitivity | 5/5 | 4/5 | 4/5 | 5/5 | 5/5 |
Specificity | 4/4 | 4/4 | 4/4 | 2/4 | 1/4 |
Accuracy | 9/9 | 8/9 | 8/9 | 7/9 | 6/9 |