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Table 1 DENV detection in blood donations collected in Puerto Rico in 2007

From: Immunologic hypo- or non-responder in natural dengue virus infection

  S/CO by TMA* S/CO by eTMA CDC Testing
Unit Initial Retest Initial Retest Serotype$ Viral load (Copies/ml) C6/36# Anti-DENV IgM
1 27.75 38.99 87.16 88.52 DENV-2 1.12 × 109 Pos Neg
2 32.34 33.30    DENV-2 5.08 × 108 Pos Pos
3& 33.30 37.38 91.10 83.09 DENV-2 1.35 × 108 Pos Neg
4 37.66 39.16 87.13 89.32 DENV-3 7.25 × 107 Pos Neg
5 40.29 27.03 82.29 92.04 DENV-3 1.37 × 107 Pos Neg
6 32.73 35.03    DENV-3 1.18 × 107 Pos Neg
7 33.91 32.87    DENV-3 7.67 × 106 Pos Neg
8 31.97 30.59    DENV-1 4.49 × 106 Pos Neg
9 19.14 13.94    DENV-2 2.82 × 106 Pos Pos
10 33.10 38.68 87.86 89.91 DENV-3 6.39 × 105 Pos Neg
11 31.25 33.56    DENV-3 3.50 × 105 Pos Neg
12 5.68 20.55 29.48 21.59 DENV-3 1.00 × 105 Pos Neg
13 34.81 37.21 76.16 32.72   <103 Neg Neg
14 23.38 31.07 31.25 31.18   <103 Neg Neg
15 14.23 23.26 28.59 3.28   <103 Neg Pos
16 13.14 25.77 29.26 12.51   <103 Neg Neg
17 11.51 5.63     <103 Neg Neg
18 8.17 16.58     <103 Neg Neg
19 6.64 8.91     <103 Neg Pos
20 5.06 4.12 29.96 8.61   <103 Neg Neg
21 3.37 4.95     <103 Neg Pos
22 2.95 25.28     <103 Neg Pos
23 8.20 1.40     <103 Neg Neg
24 4.46 0.01 24.80 0.06   <103 Neg Neg
25 1.02 2.29 28.01 0.01   <103 Neg Neg
26% 0.45   26.38 27.55   <103 Neg Neg
27% 0.17   26.18 30.99   <103 Neg Neg
28% 0.30   25.31 29.11   <103 Neg Neg
29% 0.50   24.34 17.85   <103 Neg Neg
  1. *TMA reactive when the S/CO ratio is 1.00 or greater. $Serotype-specific, real-time RT-PCR. #C6/36=the mosquito cell line used for infectivity studies. &Unit3 was involved in a transfusion transmission. %Four TMA nonreactive samples were eTMA reactive. Bold text indicates positive values. With permission from originally published in Transfusion 2012 Aug; 52(8):1657-66.
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Journal of Biomedical Science

ISSN: 1423-0127