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Figure 5 | Journal of Biomedical Science

Figure 5

From: Involvement of STIM1 and Orai1 in EGF-mediated cell growth in retinal pigment epithelial cells

Figure 5

Knockdown of Orai1 and STIM1 reduced the EGF-mediated cell proliferation and migration in ARPE-19 cells. (A i, ii) ARPE-19 cells were transfected with Orai1 and STIM1 siRNA. Expression of Orai1 and STIM1 was detected by real-time PCR (i) and Western blots (ii). (B-C) ARPE-19 cells transfected with Orai1 and STIM1 siRNA suppressed the 25 ng/mL EGF-induced cell proliferation and migration. WST-1 assay or cell migration assay was used in the study. (D) Quantitative analysis of cell migration of FigureĀ 5C.

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