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Table 2 Association analyses of EGFRvIII expressing status with the other factors

From: Dissecting the EGFR-PI3K-AKT pathway in oral cancer highlights the role of the EGFR variant III and its clinical relevance

 

EGFRvIII expression

 
 

Total

Negative or low

High

P-value

Staging

    

T classification#

108

   

 1

38

35

3

<0.001

 2

36

20

16

 

 3

6

4

2

 

 4

28

15

13

 

N classification

108

   

 0

72

53

19

0.071

 1

15

11

4

 

 2

21

10

11

 

TNM stage

108

   

 1

30

29

1

<0.001

 2

24

13

11

 

 3

13

10

3

 

 4

41

22

19

 

Factors

    

EGFR GCN amplification

104

   

 Negative

53

38

15

0.529

 Positive

51

33

18

 

EGFR expression

108

   

 Negative

39

27

12

1.000

 Positive

69

47

22

 

PIK3CA GCN increase

105

 

1.000

 

 Negative

79

53

26

 

 Positive

26

18

8

 

PTEN expression

108

   

 Negative

53

41

12

0.064

Positive

55

33

22

 

pAKT expression#

107

   

 Negative

14

11

3

0.543

 Positive

93

63

30

 
  1. P-value was estimated using chi-square method or #Fisher’s exact test.
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Journal of Biomedical Science

ISSN: 1423-0127