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Table 2 Association analyses of EGFRvIII expressing status with the other factors

From: Dissecting the EGFR-PI3K-AKT pathway in oral cancer highlights the role of the EGFR variant III and its clinical relevance

  EGFRvIII expression  
  Total Negative or low High P-value
Staging     
T classification# 108    
 1 38 35 3 <0.001
 2 36 20 16  
 3 6 4 2  
 4 28 15 13  
N classification 108    
 0 72 53 19 0.071
 1 15 11 4  
 2 21 10 11  
TNM stage 108    
 1 30 29 1 <0.001
 2 24 13 11  
 3 13 10 3  
 4 41 22 19  
Factors     
EGFR GCN amplification 104    
 Negative 53 38 15 0.529
 Positive 51 33 18  
EGFR expression 108    
 Negative 39 27 12 1.000
 Positive 69 47 22  
PIK3CA GCN increase 105   1.000  
 Negative 79 53 26  
 Positive 26 18 8  
PTEN expression 108    
 Negative 53 41 12 0.064
Positive 55 33 22  
pAKT expression# 107    
 Negative 14 11 3 0.543
 Positive 93 63 30  
  1. P-value was estimated using chi-square method or #Fisher’s exact test.