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Figure 7 | Journal of Biomedical Science

Figure 7

From: Mitofusion-2-mediated alleviation of insulin resistance in rats through reduction in lipid intermediate accumulation in skeletal muscle

Figure 7

MFN2 overexpression increased CPT1 mRNA and protein expression in rat skeletal muscle, but had no significant effects on muscle CD36 expression. Rats were fed with high-fat diets for 8 weeks, and then were infected with Ad-MFN2 (109 v.p./kg body weight) or empty Ad adenoviruses or PBS control for 3 weeks. The expression levels of CD36 (A, B, C) and CPT1 (D, E, F) were measured by Real-time PCR and Western blot. *P < 0.05, **P < 0.01, compared with Ad, n = 6.

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