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Figure 7 | Journal of Biomedical Science

Figure 7

From: The cAMP effector EPAC activates Elk1 transcription factor in prostate smooth muscle, and is a minor regulator of α1-adrenergic contraction

Figure 7

Effects of OME and pCPT on the content of phospho-Elk1 in human prostate tissue. Samples from one prostate were incubated for 2 h with OME (30 μM), pCPT (30 μM), or water (solvent), and subsequently analyzed for phospho-Elk1, total Elk1, pan-cytokeratin, PSA, and β-actin by Western blot analysis. Shown are representative Western blots in (A), and densitometric quantification in (B) from experiments with prostates from n=6 (phospho-Elk) patients (* p<0.0007 vs. H2O).

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