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Table 1 Association of TS protein expression with clinicopathological data from patients with NSCLC

From: Association of thymidylate synthase gene 3'-untranslated region polymorphism with sensitivity of non-small cell lung cancer to pemetrexed treatment: TS gene polymorphism and pemetrexed sensitivity in NSCLC

Characteristic n Positive expression of TS protein Positivity (%) χ2 P
Age (years)
 < 60 72 45 63 1.1 0.29
 ≥ 60 88 62 70
Gender
 Male 84 51 61 3.0 0.08
 Female 76 56 74   
Disease stage
 IIIB 108 75 69 1.0 0.32
 IV 52 32 62
ECOG grade
 0 48 28 58 2.4 0.31
 1 74 53 72   
 2 38 26 68   
Histology
 Squamous cell carcinoma 41 34 83 6.4 0.01
 Adenocarcinoma 119 73 61