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Table 3 Multivariate analysis of patientssurvival according to clinicopathological data and TS gene 3’-UTR 1494 bp polymorphisms

From: Association of thymidylate synthase gene 3'-untranslated region polymorphism with sensitivity of non-small cell lung cancer to pemetrexed treatment: TS gene polymorphism and pemetrexed sensitivity in NSCLC

  Regression coefficient (b) Standard errors Wald P Exp (b) 95% CI
Gender −0.31 0.22 2.0 0.16 0.73 0.48-1.1
Age 0.61 0.22 7.5 0.01 1.8 2.0-2.8
Tumor stage 0.77 0.24 11 0.00 2.1 1.4-3.5
ECOG grade −0.27 0.16 2.8 0.10 0.80 0.55-1.1
Genotype 0.92 0.27 12 0.01 2.5 1.5-4.3
Positive expression of TS protein −0.60 0.28 4.6 0.03 0.55 0.32-1.0