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Table 3 Multivariate analysis of patientssurvival according to clinicopathological data and TS gene 3’-UTR 1494 bp polymorphisms

From: Association of thymidylate synthase gene 3'-untranslated region polymorphism with sensitivity of non-small cell lung cancer to pemetrexed treatment: TS gene polymorphism and pemetrexed sensitivity in NSCLC

 

Regression coefficient (b)

Standard errors

Wald

P

Exp (b)

95% CI

Gender

−0.31

0.22

2.0

0.16

0.73

0.48-1.1

Age

0.61

0.22

7.5

0.01

1.8

2.0-2.8

Tumor stage

0.77

0.24

11

0.00

2.1

1.4-3.5

ECOG grade

−0.27

0.16

2.8

0.10

0.80

0.55-1.1

Genotype

0.92

0.27

12

0.01

2.5

1.5-4.3

Positive expression of TS protein

−0.60

0.28

4.6

0.03

0.55

0.32-1.0