Figure 3From: Cysteine-rich domain of scavenger receptor AI modulates the efficacy of surface targeting and mediates oligomeric Aβ internalizationSchematic representation of human SR-AI, SR-AII, and SR-AI variants. Constructs 430, 407, 371, and 341 were SR-AI variants with truncated SRCR domains. Construct 341wirh exon 11 fused to the C-terminus of the collagenous domain mimicking SR-AIII is designated as 341-ex 11. * indicates three lysine residues in the collagenous domain that were mutated to alanine at 332, 335, 338 in 341KA and SR-AIKA. Seven putative N-glycosylation sites in the spacer and coiled coil domains of SR-AI were labeled.Back to article page