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Table 1 The IC 50 of CC-EW and CCB for Aβ-mediated changes on microglia

From: Cudrania cochinchinensis attenuates amyloid β protein-mediated microglial activation and promotes glia-related clearance of amyloid β protein

Stimuli

Component

IC50(μg/ml or μM)a

Nitric oxide

iNOS expression

Form factor

Aβ deposition

IFN-γ

CC-EW

58.28 ± 6.73

nd

nd

nd

IFN-γ + Aβ

CC-EW

12.83 ± 3.36

40.83 ± 5.66

30.00 ± 3.65

32.67 ± 2.69

 

CCB

11.01 ± 1.02

11.37 ± 1.63

10.02 ± 2.11

17.82 ± 1.78

  1. a. The unit for IC50 is μg/ml for CC-EW and μM for CCB.
  2. nd means not determined.
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Journal of Biomedical Science

ISSN: 1423-0127