Table 6 Multivariate analyses (cox regression) of overall survival a in younger and older patients
Variables | Patients ≦ 60 y/o | Patients > 60 y/o | ||||||
|---|---|---|---|---|---|---|---|---|
95% CI | 95% CI | |||||||
HR | Lower | Upper | P | HR | Lower | Upper | P | |
NPM1 b | 0.000 | 0.000 | 1.490E89 | 0.898 | 0.263 | 0.021 | 3.377 | 0.305 |
FLT3- ITDc | 7.505 | 1.538 | 36.614 | 0.013* | 3.235 | 0.424 | 24.699 | 0.258 |
FLT3- TKD | 9765.104 | 32.249 | 2.95E6 | 0.002* | 144.617 | 0.000 | 3.75E169 | 0.980 |
CEBPA d | 0.357 | 0.125 | 1.020 | 0.054 | 1.090 | 0.292 | 4.066 | 0.898 |
IDH1 b | 14220.871 | 0.000 | 3.9E99 | 0.932 | 174.990 | 0.000 | 4.56E169 | 0.979 |
IDH2 b | 0.000 | 0.000 | 2.695E210 | 0.958 | 0.459 | 0.050 | 4.242 | 0.492 |
DNMT3A b | 146.313 | 0.000 | 4.16E97 | 0.965 | ||||
MLL b | 0.059 | 0.000 | 1.78E94 | 0.980 | 2.245 | 0.173 | 29.122 | 0.536 |
MN1 e | 1.923 | 1.130 | 3.273 | 0.016* | 1.198 | 0.916 | 1.567 | 0.187 |
ERG | 53.777 | 1.820 | 1589.377 | 0.021* | 32.349 | 2.889 | 362.237 | 0.005* |
miR-181a | 0.514 | 0.260 | 1.014 | 0.055 | 1.361 | 0.933 | 1.986 | 0.110 |
miR-3151 | 1.164 | 0.580 | 2.337 | 0.669 | 0.423 | 0.191 | 0.935 | 0.033* |
BDH2 e | 4.829 | 1.002 | 23.274 | 0.050* | 18.937 | 1.571 | 228.308 | 0.021* |