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Table 1 Serum and urine levels of potassium, phosphate, bicarbonate, uric acid, and glucose in the TDF treated rats and control rats

From: Depletion of the cellular antioxidant system contributes to tenofovir disoproxil fumarate - induced mitochondrial damage and increased oxido-nitrosative stress in the kidney

Parameter

Control

Test

 

(n = 6)

(n = 6)

Serum

  

Phosphate ( mmol/L)

5.88 ± 0.78

4.10 ± 0.36*

Potassium (mmol/L)

6.31 ± 0.47

5.58 ± 0.51*

Uric Acid (mg%)

1.53 ± 0.35

2.9 ± 1.3

Glucose (mg%)

94.33 ± 12.6

90.8 ± 15.4

Urine

  

Bicarbonate (mmol/L)

0.25 ± 0.058

2.56 ± 1.21**

Uric acid (mg/100 mL)

5.1 ± 1.69

12.9 ± 5.0**

Potassium ( mmol/L)

2.68 ± 1.3

10.38 ± 2.9**

Phosphate ( mmol/L)

0.27 ± 0.1

4.68 ± 1.52*

  1. Values are represented as Mean ± S.D., n = number of rats. * P < 0.05, ** P < 0.01 vs. control.