Figure 4From: Inhibition of actin polymerization decreases osteogeneic differentiation of mesenchymal stem cells through p38 MAPK pathwayEffect of CYD treatment on osteogenic differentiation. Percentage of ALP positive cells (A,B) or OSTEOCALCIN (C) expression in MSC induced to undergo osteogeneis without (CONTROL) or with CYD (+CYD) treatment. CYD treatment was given for initial one day (1D) during 3 days of osteogenic induction (A) or for initial 3 days (3D) during 7 days osteogenesis induction (B,C). F-actin staining with phalloidin-TRITC of CYD treated MSC in each condition is shown in the inset. Values are mean ± SD, n = 3-4. ** P < 0.005, *** p < 0.0005, ALP stands for alkaline phosphatase.Back to article page