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Table 3 Concentration of some biochemical parameters between 1 st visit (baseline) and 3 rd visit in HIV + subjects undergoing ART

From: Biochemical and haematological changes in HIV subjects receiving winniecure antiretroviral drug in Nigeria

Parameters 1stvisit 3rdvisit Reference value P-value
AST (U/l) 31.66 ± 25.20a 34.31 ± 52.21b 25 ± 80c P < 0.001
ALT/(U/l) 21.38 ± 14.26a 38.47 ± 22.66b 20 ± 12.2a P < 0.0001
ALP (U/l) 88.4 ± 21.31a 97.31 ± 29.1b 62 ± 11c P < 0.05
Amylase (U/l) 59.43 ± 42.62a 71.21 ± 41.26b 80 ± 25.31b P > 0.05
Plasma urea (mmol/l) 4.17 ± 8.22a 4.21 ± 13.64a 4.3 ± 10a P < 0.002
Plasma creatinine (mmol/l) 1.20 ± 0.99a 1.10 ± 1.01a 1.23 ± 0.9a P < 0.629
Direct bilirubin (mg/dl) 0.19 ± 0.10a 0.21 ± 0.11b 0.18 ± 0.07a P < 0.001
Albumin (U/l) 3.3 ± 2.3a 3.02 ± 2.8a 4.2 ± 1.1b P < 0.002
  1. Data on 1st and 3rd visits were compared against the reference values using ANOVA at a 5% level of significance. Reference values are values obtained from the HIV negative healthy control group. Data with different superscript a,b and c indicates significant difference.