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Table 3 Concentration of some biochemical parameters between 1 st visit (baseline) and 3 rd visit in HIV + subjects undergoing ART

From: Biochemical and haematological changes in HIV subjects receiving winniecure antiretroviral drug in Nigeria

Parameters

1stvisit

3rdvisit

Reference value

P-value

AST (U/l)

31.66 ± 25.20a

34.31 ± 52.21b

25 ± 80c

P < 0.001

ALT/(U/l)

21.38 ± 14.26a

38.47 ± 22.66b

20 ± 12.2a

P < 0.0001

ALP (U/l)

88.4 ± 21.31a

97.31 ± 29.1b

62 ± 11c

P < 0.05

Amylase (U/l)

59.43 ± 42.62a

71.21 ± 41.26b

80 ± 25.31b

P > 0.05

Plasma urea (mmol/l)

4.17 ± 8.22a

4.21 ± 13.64a

4.3 ± 10a

P < 0.002

Plasma creatinine (mmol/l)

1.20 ± 0.99a

1.10 ± 1.01a

1.23 ± 0.9a

P < 0.629

Direct bilirubin (mg/dl)

0.19 ± 0.10a

0.21 ± 0.11b

0.18 ± 0.07a

P < 0.001

Albumin (U/l)

3.3 ± 2.3a

3.02 ± 2.8a

4.2 ± 1.1b

P < 0.002

  1. Data on 1st and 3rd visits were compared against the reference values using ANOVA at a 5% level of significance. Reference values are values obtained from the HIV negative healthy control group. Data with different superscript a,b and c indicates significant difference.