Histopathological findings of infarct area by day 21 after AMI. A) Illustrations of trimethyl tetrazolium chloride (TTC) staining of the left ventricular (LV) infarct area at basal, middle and apical areas by day 21 after AMI induction. B) Statistical analysis showed significantly lower infarct area at basal, middle and apical levels of left ventricle in AMI + Tac group than in AMI group (all p values <0.05). C) Quantification of wall thickness in infarct area. * vs. †, p<0.05. Tac = tacrolimus. (n=6 for each group).