Figure 9From: Innate immune response after acute myocardial infarction and pharmacomodulatory action of tacrolimus in reducing infarct size and preserving myocardial integrityProtein expressions of myocardial integrity biomarkers of mitochondrial cytochrome C, connexin43 and γ-H2AX in infarct area (IA) and peri-IA by day 21 after AMI induction. A) protein expression of mitochondrial cytochrome C in IA. * vs. other bars with different symbols, p<0.005. B) protein expression of mitochondrial cytochrome C in peri-IA. * vs. other bars with different symbols, p<0.01. C) protein expression of connexin43 (Cx43) in IA. * vs. other bars with different symbols, p<0.01. D) protein expression of Cx43 in peri-IA. * vs. other bars with different symbols, p<0.01. E) Protein expression of γ-H2AX in IA. * vs. other bars with different symbols, p<0.001. F) Protein expression of γ-H2AX in peri-IA. * vs. other bars with different symbols, p<0.001. All statistical analyses using one-way ANOVA, followed by Bonferroni multiple comparison post hoc test. Symbols (*, †, ‡) indicate significance (at 0.05 level). NC = normal control; AMI = acute myocardial infarction; Tac = tacrolimus. (n=6 for each group).Back to article page