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Figure 9 | Journal of Biomedical Science

Figure 9

From: Innate immune response after acute myocardial infarction and pharmacomodulatory action of tacrolimus in reducing infarct size and preserving myocardial integrity

Figure 9

Protein expressions of myocardial integrity biomarkers of mitochondrial cytochrome C, connexin43 and γ-H2AX in infarct area (IA) and peri-IA by day 21 after AMI induction. A) protein expression of mitochondrial cytochrome C in IA. * vs. other bars with different symbols, p<0.005. B) protein expression of mitochondrial cytochrome C in peri-IA. * vs. other bars with different symbols, p<0.01. C) protein expression of connexin43 (Cx43) in IA. * vs. other bars with different symbols, p<0.01. D) protein expression of Cx43 in peri-IA. * vs. other bars with different symbols, p<0.01. E) Protein expression of γ-H2AX in IA. * vs. other bars with different symbols, p<0.001. F) Protein expression of γ-H2AX in peri-IA. * vs. other bars with different symbols, p<0.001. All statistical analyses using one-way ANOVA, followed by Bonferroni multiple comparison post hoc test. Symbols (*, †, ‡) indicate significance (at 0.05 level). NC = normal control; AMI = acute myocardial infarction; Tac = tacrolimus. (n=6 for each group).

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