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Figure 4 | Journal of Biomedical Science

Figure 4

From: DNA transposon-based gene vehicles - scenes from an evolutionary drive

Figure 4

Homology-dependent DNA repair by synthesis-dependent strand annealing (SDSA). Following excision, the 3′-DNA termini from the double-stranded breaks invade the homologous sequence on the sister chromatid. The homologous sequence is then used as template for DNA synthesis and the final, elongated 3′-DNA termini anneal to each other and are joined with the 5′ ends by ligation.

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