Figure 5
From: DNA transposon-based gene vehicles - scenes from an evolutionary drive
Transposon regulation by RNA interference. (A) An upstream promoter (UP) generates read-through transcripts that fold back on themselves due to intramolecular base pairing of the inverted repeats (IRs), thereby generating dsRNA transcripts that may be processed into RNAi effectors. (B) Upstream and downstream promoters (DP) create bi-directional RNA transcripts that anneal and form dsRNA. (C) Promoter-like activity in the inverted repeats generates sense and antisense transcripts which, as in (B) anneal to form dsRNA.