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Table 1 DNA transposon vectors and their main characteristics

From: DNA transposon-based gene vehicles - scenes from an evolutionary drive

Transposon Transposon family Target sequence Integration preference Cargo capacity Footprint Overproduction inhibition Hyperactive transposase References
Sleeping Beauty Tc1/mariner TA Fairly random (31-39% into genes) ~ 10 kb C(A/T)GTA Yes SB100X [5054]
Frog Prince Tc1/mariner TA ND ND C(A/T)GTA ND None [30]
Hsmar1 Tc1/mariner TA Fairly random (44% into genes) ND T(T/A)A Yes None [34, 55, 56]
Himar1 Tc1/mariner TA Fairly random 4 kb ACTA Yes C9 [31, 5759]
Passport Tc1/mariner TA Transcriptional units (63% into genes) ND ND Yes None [33]
Tol2 hAT 8 bp random sequence Transcriptional units (39-48% into genes) > 11 kb 8 bp random sequence Limited None [6062]
TcBuster hAT 8 bp random sequence Transcriptional units ND 8 bp random sequence ND TcBusterCOV596A [36, 37]
PiggyBac PiggyBac TTAA Transcriptional units (47-67% into genes) 100 kb None Conflicting reports 7pB, hyPBase [2729, 63, 64]
PiggyBat PiggyBac TTAA Transcriptional units ND ND ND None [35]
  1. ND: Not determined.