Figure 5
Effects of leptin on the transient outward current ( I to ), the ultra-rapid delayed rectifier potassium current ( I Kur ) and the inward rectifier potassium current ( I K1 ) in left atrial (LA) myocytes. A. Examples and I–V relationship of the Ito from control (n = 11) and leptin-treated (n = 16) LA myocytes. B. Examples and I–V relationship of the IKur from control (n = 12) and leptin-treated (n = 14) LA myocytes. C. Examples and the I–V relationship of the IK1 from control (n = 8) and leptin-treated (n = 10) LA myocytes. The inset in the current traces shows the clamp protocol. *p < 0.05; ***p < 0.005 versus control LA myocytes.