Figure 2

In vivo effect of BBD on the cerebral ischemia. SD rats treated with BBD i.p. 90 min after MACO had reduced infarct sizes of brains (A). Data are expressed as mean ± SEM. *: P < 0.05 as compared to the non-treated ischemic control. (n = 8). SOD activity and lipid peroxidation were determined by commercial assay kits (Cayman, Ann Arbor, MI, USA). Malondialdehyde (MDA) of SD rats was increased by ischemic stress but reduced by BBD (B) and SOD activity was restored by BBD (C). Data are expressed as mean ± SEM. *: P < 0.05 as compared to the hypoxia control. (n = 4).