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Table 1 The PAMPA-BBB permeation of BBD

From: Protective effect of a sesamin derivative, 3-bis (3-methoxybenzyl) butane-1, 4-diol on ischemic and hypoxic neuronal injury

Compound Pe (10-6 cm/s) Known Pe (10-6 cm/s) Classification
Theophylline 0.08 ± 0.01 0.12 ~ 0.18 BBB-
Verapamil 23.82 ± 1.82 16 ~ 23 BBB+
Testosterone 34.08 ± 4.78 17 BBB+
BBD 20.87 ± 3.05 - BBB+
Sesamin 0.00 ± 0.01 - BBB-