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Figure 1 | Journal of Biomedical Science

Figure 1

From: Inhibition of the phosphoinositide 3-kinase pathway decreases innate resistance to lipopolysaccharide toxicity in TLR4 deficient mice

Figure 1

Survival study. (A) Survival rate of the C57BL/6 mice receiving intraperitoneal injections of 100, 500, or 1000 μg LPS from Escherichia coli serotype 026:B6. Mice were monitored up to 7 days (n = 10 in each group) (B) Survival rate of the Tlr4-/- mice receiving intraperitoneal injection of LY294002 (1 mg/25 g body weight) alone, 500 μg LPS alone, or 500 μg LPS with LY294002 injected 1 h prior.

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Journal of Biomedical Science

ISSN: 1423-0127