Figure 2From: Inhibition of the phosphoinositide 3-kinase pathway decreases innate resistance to lipopolysaccharide toxicity in TLR4 deficient mice Akt phosphorylation and p65 nuclear translocatoin in the lung, liver, and spleen tissues of C57BL/6 and Tlr4 -/- mice at 3 and 6 h after intraperitoneal injection of 500 μg LPS in the absence or presence of LY294002 injected 1 h prior in quadruplicate. Back to article page