Figure 2

Tryptase inhibits U87 cell apoptosis. The treatment of U87 cells is denoted above each dot plot panel. Radiation: U87 cells were treated with radiation (8Gy) in the culture. Dose of tryptase (control peptide and active peptide): 10 μg/ml. A, the dot plots indicat the frequency of PI⁺ U87 cells or/and Annexin V⁺ cells, which are summarized in B. PAR2d: U87 cells with the PAR2 gene knockdown. cshRNA: U87 cells treated with control shRNA. C, the PAR2 gene knockdown results. *, p < 0.01, compared with group A7 (mean ± SD). The data are from 3 separate experiments.