Skip to main content
Figure 3 | Journal of Biomedical Science

Figure 3

From: Shear-induced endothelial mechanotransduction: the interplay between reactive oxygen species (ROS) and nitric oxide (NO) and the pathophysiological implications

Figure 3

Devices used to carry out in vitro studies to examine the influence of flow (shear stress) on ECs. (A) Parallel-plate flow chamber. In a parallel-plate flow chamber system ECs monolayers are exposed to well-defined flow and thus shear stress (denoted by Ï„) in a small channel with fixed height. (B) Cone-and-plate flow chamber. In a cone-and-plate flow chamber system ECs monolayers are exposed to shear stress (Ï„) generated by a rotating cone. The magnitude of shear stress can be calculated using the respective formula shown in A and B.

Back to article page