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Figure 4 | Journal of Biomedical Science

Figure 4

From: Attenuated neuroprotective effect of riboflavin under UV-B irradiation via miR-203/c-Jun signaling pathway in vivo and in vitro

Figure 4

RF and UV-B-RF have differential effects on DNA damage and caspase-3 activation in the cortical region of brain subjected to ischemic injury. Immunoblotting analysis of (A) p-H2AX and (B) Cleaved caspase-3 in cell lysates prepared from the cortical regions of the brain subjected to ischemic injury and pretreated with either vehicle (saline), RF (10 mg/kg i.p.), UV-B-RF(10 mg/kg, i.p.) or miR-203 mimic (200 nM/kg i.p.). Representative images of at least three independent experiments are shown.

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