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Table 1 Effect of RF and UV-B-RF treatment on differential expression of miRNAs cerebral cortex in vivo and cortical neuronal culture in vitro

From: Attenuated neuroprotective effect of riboflavin under UV-B irradiation via miR-203/c-Jun signaling pathway in vivo and in vitro

Expression of miRNAs in rat cerebral cortex treated RF and UV-B-RF

miRNAs

RF Pre- treatment (Fold Change)

P Value

UV-B irradiated RF-pre treatment (Fold Change)

P Value

miR-203

3.50

0.05

0.50

0.05

miR-23a

1.10

0.30

1.20

0.25

miR-10b

1.20

0.40

1.10

0.30

miR-145

1.20

0.60

1.10

0.35

miR-350

1.30

0.45

1.20

0.50

miR-27a

0.90

0.64

0.80

0.49

Expression of miRNAs in rat primary cortical neurons treated with RF and UV-B-RF

miR-203

4.9

0.05

0.25

0.05

miR-23a

-1.2

0.06

-0.80

0.25

miR-10b

-1.3

0.20

-1.10

0.30

miR-145

1.1

0.40

0.94

0.35

miR-350

1.4

0.35

1.10

0.50

miR-27a

-1.3

0.44

-1.20

0.49

  1. miR-203 expression level increases significantly (p<.05) in cortical brain tissue and neuronal culture.