Association between risk of oral precancer and genetic variations in microRNA and related processing genes

Table 3 MDR interaction analysis between loci and tobacco habits in “leukoplakia vs control” group

Best predictive interactive model^a	TBA^b	CVC^c	1000 permutation p value^d
PY CY mir196a2	0.67	9	<0.001
PY CY mir34b mir29a	0.67	10	<0.001
PY CY mir29a mir34b mir423 Xpo5	0.62	9	<0.002

^aBest model was selected as one with minimum prediction error, maximum CVC and significant p-value after 1000 permutation.
^bTBA corresponds to testing balanced accuracy, the accuracy with which the model can predict disease status.
^cCross Validation Consistency: calculated out of 10.
^dp value calculated after running 1000 permutations in MDR-pt program.