Figure 6
From: Visfatin induces MUC8 and MUC5B expression via p38 MAPK/ROS/NF-κB in human airway epithelial cells
The role of NF-κB in visfatin-induced MUC8 and MUC5B expression in NCI-H292 cells. (A) Western blot analysis showed that visfatin significantly activated the phosphorylation of NF-κB. (B) RT-PCR showed that PDTC significantly attenuated visfatin-induced MUC8 and MUC5B mRNA expression. Images are representative of three separate experiments performed in triplicate. Bars indicate the mean ± S.D. of three independent experiments performed in triplicate. *P < 0.05 compared with zero value. **P < 0.05 compared with visfatin alone.