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Table 2 The relationship of DNMT1 expression with the number of methylated genes

From: Promoter methylation analysis of WNT/β-catenin pathway regulators and its association with expression of DNMT1 enzyme in colorectal cancer

Number of methylated genes

DNMT1-overexpressed cases

Odds ratio (CI 95%)

N (%)

Fold change (mean ± SD)

1 (n = 35)

13 (37.1)

1.52 ± 1.12

1

2 (n = 19)

11 (57.9)

2.12 ± 1.56

2.3 (0.7-7.2)

3 (n = 16)

9 (56.2)

2.02 ± 1.78

2.1 (0.6-7.2)

4 (n = 10)

6 (60)

3.61 ± 1.89

2.5 (0.6-10.7)

5 (n = 11)

7 (63.6)

3.06 ± 1.55

2.9 (0.7-12.9)

6 (n = 7)

6 (85.7)

4.14 ± 1.28

10.1 (1.1-93.9)*

  1. *p value <0.05, CI, confidence interval.