Pin1 positively affects tumorigenesis of esophageal squamous cell carcinoma and correlates with poor survival of patients

Table 1 The correlation between clinicopathologic characteristics and Pin1 expression

Characteristics	Total	Pin1 low (n = 39)	Pin1 high (n = 50)	P-value
Age (yrs)	33-81	37-81	33-80
	(Median: 62)	(Median: 63)	(Median: 62)
≦62	46	20	26	1.000
>62	43	19	24
Sex
Male	84	36	48	0.650
Female	5	3	2
TNM classification
T
T1-2	41	23	18	0.035
T3-4	48	16	32
N
N0	39	20	19	0.282
N1	50	19	31
M
M0	87	39	48	0.502
M1	2	0	2
Stage				0.047
I-II	55	29	26	0.047
III-IV	34	10	24

Patients with moderately and strongly positive Pin1 levels were categorized into the high Pin1 group. Patients with equivocal and weakly positive Pin1 levels were included in the low Pin1 group.

ISSN: 1423-0127