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Table 2 Urinary biochemistry profile

From: Recombinant Lactobacillus plantarum expressing and secreting heterologous oxalate decarboxylase prevents renal calcium oxalate stone deposition in experimental rats

Daysα Group I (n = 6) Group II Group III Group IV Group V
Bodyweight (g)      
0 140.40 ± 1.24 130.70 ± 3.18 131.01 ± 3.42 133.57 ± 2.66 133.38 ± 2.27
7 173.49 ± 2.34 134.37 ± 2.01a* 145.59 ± 2.82a* 142.27 ± 3.70a* 140.42 ± 2.10a*
14 218.31 ± 3.32 151.16 ± 2.64 160.88 ± 2.69 164.90 ± 3.38 150.82 ± 3.01
21 240.39 ± 2.75 171.17 ± 3.04 180.17 ± 3.25 190.76 ± 3.39 171.42 ± 3.35
28 261.11 ± 2.87 195.13 ± 3.70a* 191.80 ± 2.06a* 220.14 ± 2.68a* b*c* 201.73 ± 2.51a* b*c*
Urine pH      
0 7.07 ± 0.11 6.83 ± 0.26 6.84 ± 0.19 6.74 ± 0.25 6.54 ± 0.15
7 7.13 ± 0.16 7.08 ± 0.18 6.94 ± 0.20 7.11 ± 0.18 7.29 ± 0.12
14 7.10 ± 0.22 6.94 ± 0.30 6.94 ± 0.24 6.97 ± 0.20 7.02 ± 0.15
21 7.21 ± 0.15 6.44 ± 0.19a* 6.55 ± 0.12a* 6.86 ± 0.21b*c* 6.94 ± 0.16
28 7.25 ± 0.11 6.09 ± 0.07a* 6.16 ± 0.08a* 6.90 ± 0.17a* b*c* 6.79 ± 0.13a* b*c*
Uric acid (mg/24 h)      
0 0.05 ± 0.01 0.09 ± 0.01 0.06 ± 0.01 0.05 ± 0.01 0.05 ± 0.01
7 0.12 ± 0.01 0.14 ± 0.01 0.16 ± 0.01 0.07 ± 0.01 0.12 ± 0.04
14 0.11 ± 0.02 0.18 ± 0.01a* 0.19 ± 0.01a* 0.09 ± 0.01b*c* 0.14 ± 0.01b*c*
21 0.15 ± 0.02 0.21 ± 0.02a* 0.25 ± 0.03a* 0.11 ± 0.03b*c* 0.15 ± 0.01b*c*
28 0.17 ± 0.02 0.46 ± 0.02a* 0.39 ± 0.03a* 0.12 ± 0.01b*c* 0.18 ± 0.02b*c*
Creatinine (mg/24 h)      
0 1.33 ± 0.08 1.39 ± 0.18 1.23 ± 0.15 1.11 ± 0.11 1.16 ± 0.08
7 1.04 ± 0.06 1.50 ± 0.16a* 1.69 ± 0.26a* 1.41 ± 0.11a* 1.73 ± 0.10a*
14 1.64 ± 0.24 1.73 ± 0.13a* 2.82 ± 0.29a* 1.61 ± 0.18c* 1.95 ± 0.18c*
21 1.51 ± 0.31 2.71 ± 0.19a* 3.19 ± 0.22a* 2.07 ± 0.09a*b*c* 2.30 ± 0.16a*b*c*
28 1.77 ± 0.23 3.69 ± 0.30a* 3.52 ± 0.19a* 2.52 ± 0.14a*b*c* 3.07 ± 0.61a*c*
  1. α Data are expressed as mean ± SD. Comparisons are made against Group I (Control)a , Group II (lithiatic control)b and Group III (Non-recombinant strain)c.
  2. a*b* and c* indicates the mean value is significant at p < 0.05 against group I, II and III correspondingly. n = 6 rats each group.