Flavonoid ingredients of Ginkgo biloba leaf extract regulate lipid metabolism through Sp1-mediated carnitine palmitoyltranferase 1A up-regulation

Table 2 Sequences of wild-type and mutant CPT1A promoter constructs in mutational analysis

Name	Sequence (46 bp)^a
	–50	Sp1a	Sp1b
Wild type	gtccctGCCCCGCCCGgcctgcaggtggcaccTAGGCGGCGCgcag
Sp1a mut.	gtccctGCCTAA CCCT gcctgcaggtggcaccTAGGCGGCGCgcag
Sp1b mut.	gtccctGCCCCGCCCGgcctgcaggtggcaccTAGGTAA CGCgcag
Sp1a-b mut.	gtccctGCCTAA CCCT gcctgcaggtggcaccTAGGTAA CGCgcag

^aPutative cis-elements were indicated with capital, and introduced mutations were shown in bold.

ISSN: 1423-0127