Table 6 Logistic regression analysis to test if sex ratio among patients (0 = male patients, 1 = female patients) can be modeled by rs1128503 genotype, histological grade, tumor localization, and age of diagnosis
From: Colorectal cancer susceptibility: apparent gender-related modulation by ABCB1 gene polymorphisms
Independent variable | Ba | s.e.b | Waldc | d.f.d | Pvalue | OR (95% C.I.) |
|---|---|---|---|---|---|---|
rs1128503 | Â | Â | 9.52 | 2.00 | 0.01 | Â |
CT vs CC | -2.22 | 0.72 | 9.51 | 1.00 | 0.00 | 0.11 (0.03-0.45) |
TT vs CC | -1.45 | 0.67 | 4.67 | 1.00 | 0.03 | 0.24 (0.06-0.87) |
Grade | Â | Â | 5.27 | 2.00 | 0.07 | Â |
G2 vs G1 | -1.91 | 1.23 | 2.42 | 1.00 | 0.12 | 0.15 (0.01-1.65) |
G3 vs G1 | -1.33 | 0.61 | 4.75 | 1.00 | 0.03 | 0.26 (0.08-0.87) |
Localization | Â | Â | 1.18 | 2.00 | 0.55 | Â |
sigma vs colon | 0.61 | 0.61 | 1.02 | 1.00 | 0.31 | 1.85 (0.56-6.08) |
rectum vs colon | 0.68 | 0.75 | 0.83 | 1.00 | 0.36 | 1.98 (0.46-8.57) |
Age | -0.01 | 0.02 | 0.23 | 1.00 | 0.63 | Â |
Constant | 2.54 | 1.63 | 2.43 | 1.00 | 0.12 | Â |
Model | χ 2 = 16.86 d.f. = 7 P = 0.018 |  | ||||