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Table 8 CRC male (case) versus CRC female (control) allele and haplotype association analysis

From: Colorectal cancer susceptibility: apparent gender-related modulation by ABCB1 gene polymorphisms

M1a M2b M3c Male Female Male-Freq Fem-Freq OR (95% C.I.) Chisq Pvalue
C - - 71 41 0.68 0.47 ref. d - -
T - - 33 47 0.32 0.53 0.40 (0.23-0.73) 9.22 0.0024
- G - 66 43 0.63 0.47 ref. - -
- T - 38 49 0.37 0.53 0.50 (0.29-0.90) 5.53 0.019
- - C 60 41 0.59 0.45 ref. - -
- - T 42 51 0.41 0.55 0.56 (0.32-0.99) 3.94 0.047
C G - 63.8 34.7 0.61 0.39 ref. 9.09 0.003
C T - 7.2 6.3 0.07 0.07 0.61 (0.19-1.99) 0.00 0.99
T G - 2.2 5.3 0.02 0.06 0.22 (0.04-1.21) 1.88 0.17
T T - 30.8 41.7 0.30 0.47 0.4 (0.22-0.75) 6.61 0.010
C - C 52.5 27.9 0.52 0.32 ref. 7.68 0.0056
C - T 17.5 13.2 0.17 0.15 0.70 (0.28-1.75) 0.26 0.61
T - C 7.5 11.2 0.07 0.13 0.35 (0.11-1.13) 1.49 0.22
T - T 24.5 35.9 0.24 0.41 0.36 (0.18-0.72) 6.78 0.009
- G C 51.8 33.4 0.51 0.36 ref. 4.41 0.036
- G T 13.2 9.6 0.13 0.10 0.89 (0.33-2.39) 0.26 0.61
- T C 8.2 7.6 0.08 0.08 0.70 (0.22-2.23) 0.02 0.90
- T T 28.8 41.4 0.28 0.45 0.45 (0.24-0.86) 5.90 0.015
C G C 49.0 27.4 0.50 0.32 ref. 6.35 0.012
C G T 12.9 7.4 0.13 0.09 0.97 (0.34-2.81) 0.99 0.32
C T T 4.1 6.2 0.04 0.07 0.37 (0.10-1.45) 0.71 0.40
T G C 2.1 3.2 0.02 0.04 0.37 (0.06-2.39) 0.33 0.57
T T C 5.9 7.4 0.06 0.09 0.44 (0.13-1.58) 0.55 0.46
T T T 24.0 34.4 0.24 0.40 0.39 (0.19-0.79) 5.33 0.021
  1. aM1 1236 C > T rs1128503.
  2. bM2 2677 G > T/A rs2032582.
  3. cM3 3435 C > T rs1045642.
  4. dreference.