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Table 1 MICs and FICI of SSE, AMP when used either alone or in combination against ARSA

From: Synergistic activity and mechanism of action of Stephania suberosa Forman extract and ampicillin combination against ampicillin-resistant Staphylococcus aureus

Strains   MIC   FIC FIC index
AMP (μg/ml) SSE (mg/ml) NIS (μg/ml) AMP + SSE (μg/ml + mg/ml)  
S. aureus DMST 20651 >512R 4.0ND 16 0.15 + 2.0 <0.5
S. aureus DMST 20652 >512R 4.0ND 16 0.15 + 2.0 <0.5
S. aureus DMST 20653 >512R 4.0ND 16 0.15 + 2.0 <0.5
*S. aureus ATCC 29213 0.25S 4.0ND 0.5 NT NT
  1. S = Susceptible; R = resistant; ND = No data in CLSI; NT = not test; AMP = Ampicillin; SSE = S. suberosa crude extract; NIS = Nisin; FICI ≤ 0.5 denoting synergistic; FICI>> 0.5-4.0 denoting no interaction; FICI > 4.0 denoting antagonism; *S. aureus ATCC 29213 was used as a reference strain.