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Table 1 MICs and FICI of SSE, AMP when used either alone or in combination against ARSA

From: Synergistic activity and mechanism of action of Stephania suberosa Forman extract and ampicillin combination against ampicillin-resistant Staphylococcus aureus

Strains

 

MIC

 

FIC

FIC index

AMP (μg/ml)

SSE (mg/ml)

NIS (μg/ml)

AMP + SSE (μg/ml + mg/ml)

 

S. aureus DMST 20651

>512R

4.0ND

16

0.15 + 2.0

<0.5

S. aureus DMST 20652

>512R

4.0ND

16

0.15 + 2.0

<0.5

S. aureus DMST 20653

>512R

4.0ND

16

0.15 + 2.0

<0.5

*S. aureus ATCC 29213

0.25S

4.0ND

0.5

NT

NT

  1. S = Susceptible; R = resistant; ND = No data in CLSI; NT = not test; AMP = Ampicillin; SSE = S. suberosa crude extract; NIS = Nisin; FICI ≤ 0.5 denoting synergistic; FICI>> 0.5-4.0 denoting no interaction; FICI > 4.0 denoting antagonism; *S. aureus ATCC 29213 was used as a reference strain.
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Journal of Biomedical Science

ISSN: 1423-0127