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Table 2 Ankle/brachial index and, plasma levels of ADM, b-FGF and intercellular adhesion molecules, in all study groups

From: Study of the association of adrenomedullin and basic-fibroblast growth factors with the peripheral arterial blood flow and endothelial dysfunction biomarkers in type 2 diabetic patients with peripheral vascular insufficiency

Parameter Control N = 30 Diabetics without complications N = 30 Diabetics with Vasculopathy N = 30 P value
-Plasma ADM (pmol/ml) 2.96 ± 0.62 2.56 ± 0.5 5.66 ± 1.31*¥ P = 0.001*
P = 0.01¥
-Plasma b- FGF (pg/ml) 3.96 ± 0.6 3.56 ± 0.5 1.66 ± 0.14 P = 0.002*
P = 0.01¥
-Plasma ICAM-1 (pg/ml) 318.66 ± 35.19 349.87 ± 27.18 550.3 ± 15.4*¥ P = 0.004*
P = 0.001¥
-Plasma VCAM-1(pg/ml) 677.85 ± 17.63 690.64 ± 15.081 863 ± 32.37*¥ P = 0.001*
P = 0.001¥
-Ankle/brachial index 1.03 ± 0.08 1.06 ± 0.06 0.73 ± 0.06*¥ P = 0.003*
P = 0.001¥
  1. Results are expressed as mean ± S.D.
  2. *Significant changes in comparison to control ( P < 0.05).
  3. ¥Significant changes in comparison to diabetic Group II (P < 0.05).