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Table 2 Ankle/brachial index and, plasma levels of ADM, b-FGF and intercellular adhesion molecules, in all study groups

From: Study of the association of adrenomedullin and basic-fibroblast growth factors with the peripheral arterial blood flow and endothelial dysfunction biomarkers in type 2 diabetic patients with peripheral vascular insufficiency

Parameter

Control N = 30

Diabetics without complications N = 30

Diabetics with Vasculopathy N = 30

P value

-Plasma ADM (pmol/ml)

2.96 ± 0.62

2.56 ± 0.5

5.66 ± 1.31*¥

P = 0.001*

P = 0.01Â¥

-Plasma b- FGF (pg/ml)

3.96 ± 0.6

3.56 ± 0.5

1.66 ± 0.14

P = 0.002*

P = 0.01Â¥

-Plasma ICAM-1 (pg/ml)

318.66 ± 35.19

349.87 ± 27.18

550.3 ± 15.4*¥

P = 0.004*

P = 0.001Â¥

-Plasma VCAM-1(pg/ml)

677.85 ± 17.63

690.64 ± 15.081

863 ± 32.37*¥

P = 0.001*

P = 0.001Â¥

-Ankle/brachial index

1.03 ± 0.08

1.06 ± 0.06

0.73 ± 0.06*¥

P = 0.003*

P = 0.001Â¥

  1. Results are expressed as mean ± S.D.
  2. *Significant changes in comparison to control ( P < 0.05).
  3. ¥Significant changes in comparison to diabetic Group II (P < 0.05).